Reproduction Abstracts

Epimutations are heritable defects in epigenetic programming that do not involve changes in the underlying DNA sequence and may or may not impact gene expression. Epimutations can occur naturally, but are more likely to be induced by environmental factors that disrupt the normal epigenome. Previous studies have shown that the use of assisted reproductive technologies (ART) can induce epimutations in the offspring produced. We chronicled the occurrence of epimtuations in mice p...